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Herbs & Supplements
May Apple
Scientific Name: Mayapple Other Names: American Mandrake, Bajialian, Duck's Foot, Ground Lemon, Indian Apple, Podophyllin, Podophyllum, Podophyllum peltatum, Raccoon Berry, Umbrella Plant, Wild Lemon
What side effects should I watch for?
Note: The side effects of oral podophyllum (mayapple resin) may not appear until several hours after a potentially harmful dose has been taken. Additionally, possible side effects from applying podophyllum to the skin may be similar to side effects from taking it by mouth, because chemicals in podophyllum are absorbed extensively through the skin.
Major Side Effects
Severe side effects from oral or topical podophyllum may include:
- Bloody diarrhea
- Severe stomach pain
- Hallucinations
- Muscle paralysis
- Kidney failure
- Breathing failure
- Coma
- Death
Less Severe Side Effects
Other side effects from using podophyllum on the skin may include:
- Confusion
- Headache
- Irritation at the site of application
- Low blood pressure
- Nausea
- Vomiting
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Note: The above information is not intended to replace the advice of your physician, pharmacist, or other healthcare professional. It is not meant to indicate that the use of the product is safe, appropriate, or effective for you.
In general, herbal products are not subject to review or approval by the U.S. Food and Drug Administration (FDA). They are not required to be standardized, meaning that the amounts of active ingredients or contaminants they contain may vary between brands or between different batches of the same brand. Not all of the risks, side effects, or interactions associated with the use of herbal products are known because few reliable studies of their use in humans have been done.
This information is provided for your education only. Please share this information with your healthcare provider and be sure that you talk to your doctor and pharmacist about all the prescription and non-prescription medicines you take before you begin to use any herbal product.
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